The opiate class of drugs includes heroin and morphine, both of which are derived from the resin of the opium poppy.

Heroin is quickly metabolized to morphine. Thus, morphine and morphine glucuronide may be found in the urine of a person who has only taken heroin.

The body also changes codeine to morphine. Thus, the presence of morphine (or its metabolite, morphine glucuronide) in urine may indicate heroin, morphine and/or codeine use. Therefore, positive test results do not necessarily drug abuse, as legally prescribed medications such as codeine will also test positive for opiates.

Bring tests, specimens, and/or controls to room temperature (15-30°C) before use.

1. Remove the test from its sealed pouch, and place it on a clean, level surface. Label the device with patient or control identification. For best results, the assay should be performed within one hour.

2. Add 3 drops of specimen to the specimen well (S) and start the timer.

Avoid trapping air bubbles in the specimen well (S), and do not add any solution to the result area.

As the test begins to work, color will migrate across the membrane.

3. Wait for the colored band(s) to appear. The result should be read at 5 minutes. Do not interpret the result after 8 minutes.